TIL Therapy
Tumor-Infiltrating Lymphocyte (TIL) therapy harvests the patient’s own immune cells from the tumor, expands them in the lab, and reinvigorates them to fight cancer.
50%
Response In Melanoma
FDA
Approved (Amtagvi)
ONE
Time Treatment
What is TIL Therapy?
TIL Therapy involves surgically removing a portion of the tumor, isolating these specific "fighter" cells, expanding them to billions in number in a specialized laboratory, and infusing them back into the patient to overwhelm and destroy the cancer.
Is it Suitable for All Cancers?
Current Indications
No. TIL therapy is currently used more commonly in certain solid tumors, especially metastatic melanoma. Patient suitability is determined on an individual basis by a specialized medical team.
Recent FDA milestones (e.g., Lifileucel) have marked a major breakthrough for advanced melanoma patients who have progressed after other treatments.
Main Advantages
Personalized
Uses the patient's own cells that have already successfully identified the tumor.
Polyclonal Attack
Unlike CAR-T which targets one antigen, TILs can target multiple different tumor antigens simultaneously.
Immune Strengthening
Massively boosts the number of active immune cells available to fight the cancer.
One-Time Infusion
Typically administered as a single treatment course rather than continuous cycles.
The Treatment Journey
Tumor Resection
A surgeon removes a piece of the tumor tissue.
Manufacturing (Expansion)
In the lab, TILs are isolated from the tissue and grown to billions of cells (approx. 22 days).
Conditioning
The patient receives a short course of chemotherapy to prepare the body for the new cells.
Infusion & IL-2
The TILs are infused back into the patient, followed by Interleukin-2 (IL-2) to support cell growth.
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frequently asked question
(Car-T Cell)
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What is CAR T-cell therapy?
CAR T-cell therapy is an advanced immunotherapy in which a patient’s own T cells are genetically modified to better recognize and attack cancer cells, then reinfused back into the body.
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Which cancers can be treated with CAR T-cell therapy?
It is primarily used for certain blood cancers, including specific types of leukemia and lymphoma. It is FDA-approved and shows high response rates in eligible patients.
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What is the success rate of CAR T-cell therapy?
Success varies by cancer type, but in some forms of leukemia, response rates can reach up to 90%.
(TIL Therapy)
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What is TIL therapy?
TIL (Tumor-Infiltrating Lymphocyte) therapy is an immunotherapy approach in which a patient’s own immune cells are harvested, expanded in the laboratory, and reinfused to fight cancer.
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Is TIL therapy suitable for all types of cancer?
No. TIL therapy is currently used more commonly in certain solid tumors, especially metastatic melanoma. Patient suitability is determined on an individual basis.
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What are the main advantages of TIL therapy?
Its personalized nature and its ability to strengthen the immune system in a targeted way are considered its main advantages.
